Simon is an Associate Professor in Veterinary Epidemiology and Public Health in the Melbourne Veterinary School. He teaches epidemiology into the Doctor of Veterinary Medicine, One Health breadth subjects and the Animal Health Major of the Science degree. His research focuses on modelling infectious disease outbreaks, Bayesian diagnostic test validation, zoonoses surveillance, outbreak investigation and control, with projects on COVID-19, Q fever, foot-and-mouth disease, African swine fever, Mycoplasma bovis, foodborne disease, influenzas and arboviruses. Simon is also a founding member of the World Organisation for Animal Health Collaborating Centre for Diagnostic Test Validation Science in the Asia-Pacific Region.